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The 2005 American Thoracic Society/Infectious Diseases Society of America guideline recommends combination therapy consisting of an antipseudomonal cephalosporin such as cefepime or ceftazidime, an antipseudomonal carbapenem such as imipenem or meropenem, or an extended-spectrum β-lactam/β-lactamase inhibitor such as piperacillin/tazobactam, PLUS an antipseudomonal fluoroquinolone such as levofloxacin or ciprofloxacin, or an aminoglycoside such as gentamicin, tobramycin, or amikacin, PLUS an anti-MRSA agent (vancomycin or linezolid). ΣΕ πειραματικές μελέτες valacyclovir δεν τερατογόνο δράση σε αρουραίους και κουνέλια. Systemic therapy is needed, cheap prednisone 10mg and all of the azole antifungal agents (ketoconazole, fluconazole, and itraconazole) have been used successfully [ 307, 308].

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